Endocrine Abstracts

A 51 yr old woman presented to ENT surgeons with nasal polyps. Since examination revealed a multi-nodular goitre, large hands and prognathism, acromegaly was suspected. MRI of the pituitary arranged, was normal. Two years later, nasal polyps returned. CT on this occasion showed evidence of polyps with sinusitis but again a normal pituitary fossa. She was referred to a rheumatologist for carpal tunnel symptoms, the features of acromegaly were rediscovered and she was referred t...

Klinefelter’s syndrome is the most common cause of primary testicular failure, resulting in impairment of both spermatogenesis and testosterone production. It is a chromosomal disorder characterized testosterone deficiency with elevated gonadotropin plasma levels and the treatment involves supplementing testosterone. In Klinefelter’s syndrome there is an increase of certain systemic diseases including venous thromboembolism. It is nevertheless more frequent than in a...